2. Qualitative and Quantitative Composition
Each Paxam tablet contains 0.5 mg or 2 mg of clonazepam.
Paxam tablets contain lactose.
For the full list of excipients, see section 6.1.
3. Pharmaceutical Form
Paxam 0.5 mg: peach, flat bevelled edged, 8 mm in diameter, debossed “CN” over “0.5” on one
side and cross scored on the other.
Paxam 2 mg: white, flat bevelled edged, 8 mm in diameter, debossed “CN” over “2” on one side
and cross scored on the other.
Paxam tablets may be halved and quartered.
4. Clinical Particulars
4.1 Therapeutic indications
Most clinical forms of epilepsy in infants and children, in particular typical and atypical absences
(Lennox-Gastaut syndrome), nodding spasms, primary or secondary generalised tonic-clonic
Clonazepam may also be used in epilepsy of adults and in focal seizures. Buy Paxam clonazepam 2mg online in Australia
4.2 Dose and method of administration
The dosage of clonazepam must be individually adjusted according to the patient’s clinical
response, tolerance of the medicine and the patient’s age. To ensure optimum dosage adjustment,
infants and children up to the age of 10 years should be given the 0.5 mg tablets. The cross-scored
0.5 mg tablets facilitate the administration of lower daily doses to adults in the initial stages of
treatment. Buy Paxam clonazepam 2mg online in Australia
To avoid adverse reactions at the beginning of therapy, it is essential to start treatment with
clonazepam at a low dose and increase the daily dose progressively until the maintenance dose
suited to the individual patient has been reached.
The initial dose for infants and children up to the age of 10 years (or up to 30 kg bodyweight) is
0.01-0.03 mg/kg daily given in 2-3 divided doses. The dose should be increased by no more than
0.25-0.5 mg every third day until either a daily maintenance dose of approximately 0.1 mg/kg of
bodyweight daily has been reached or seizures are controlled or undesired effects preclude further
increase. The daily maximum dose in children is 0.2 mg/kg of bodyweight and should not be
exceeded. Buy Paxam clonazepam 2mg online in Australia
Based on established dosages for children up to 10 years (see above) and those for adults (see
below) the following can be recommended for children between 10 and 16 years: The initial dose is
1-1.5 mg/day given in 2-3 divided doses. The dose may be increased by 0.25-0.5 mg every third
day until the individual maintenance dose (usually 3-6 mg/day) is reached.
The initial dose for adults should not exceed 1.5 mg/day divided into 3 doses. The dose may be
increased in increments of 0.5 mg every three days until either seizures are adequately controlled
or undesirable effects preclude any further increase. Buy Paxam clonazepam 2mg online in Australia
The maintenance dose must be individualised
for each patient depending upon response. Usually a maintenance dose of 3-6 mg per day is
sufficient. The maximum therapeutic dose for adults is 20 mg daily and should not be exceeded.
The daily dose should be divided into 3 equal doses. If doses are not equally divided, the largest
dose should be given in the evening. The maintenance dose level is best attained after 1-3 weeks
of treatment. Once the maintenance dose level has been reached, the daily amount may be given
in a single dose in the evening. Buy Paxam clonazepam 2mg online in Australia